Running head : Mental ProblemsMental ProblemsClient s NameUniversity AffiliationMental ProblemsThis article written by Shelton and Papakostas deals with the health problem of treatment-resistant depression (2008 . This refers to a situation where at least one trial of an antidepressant has bombed . More specifically , the study investigates the effectuality of atypical antipsychotics in treatment-resistant depression . This correction was chosen due to the report by the recent topic Institute of Mental Health Sequenced Treatment Alternatives to Relieve opinion (STAR D study which shows a in truth small function of people who rattling recovered as a ending of their first antidepressant treatment (Shelton Papakostas , 2008The subject of this study is very important for Health People 2010 , as it deals with the issue of effectiveness of antidepressants . The authors noted that on that point atomic number 18 several new antidepressants fixable in the market , and yet , the selective information showing responses of patients as a result of these antidepressants are dismal . For example , there are significant functional impairments found among patients who already had at least 50 improvement on the depression home plate . Moreover , despite the relatively high mean back breaker of antidepressants , the fact remains that only few people actually recover from depression (Shelton Papakostas , 2008This condition deserves adequate attention because it comprises around ten to twenty percent of people who have major depressive diss thusly , about 10-20 of depressed people fail to respond to traditional antidepressant treatments (Greenberg , et al , 2004 . Existing entropy however , do not segregate the affected community based on demographical indicators such as age and sex activity . The factors affecting this condition are not addressed by extant literature , but some research suggests ship canal of addressing the condition . Thus , in this article , it is suggested that atypical antipsychotics be used instead of traditional antidepressantsAtypical antipsychotics include drugs such as aripiprazole risperidone , olanzapine , and ziprasidone .

In to determine how these drugs are relevant to treatment-resistant depression , the authors conducted a study consisting mainly of a study and come off of clinical literature dealing with the use of such drugs to depressed patients (Shelton Papakostas , 2008From their review of clinical literature , the authors found two atypical antipsychotics that seemed declare based on controlled clinical trials . These drugs are quetiapine and olanzapine . The effectiveness of other atypical antipsychotics were either not supported by data or contradicted by a later study . Thus , the authors were not able to conclude that all atypical antipsychotics are effective for treatment-resistant depression , because existing clinical literature on the matter is decidedly mixed and unclear (Shelton Papakostas , 2008Nurses would play a significant role in the treatment of treatment-resistant depression , especially since the study showed how a lot of antidepressant medications do not work on the patients . It is noted that nursing is a handicraft that plays a very important role in the readiness of health grapple . Since nurses spend a significant issue forth of time with patients , especially when they conduct rounds and take direct care of the patients , nurses often become more familiar to the patients than the doctorsThe...If you want to get a full essay, order it on our website:
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